***For more information about this study please contact Carrie Mason, BS, RRT***
A Clinical Research Study to Understand Asthma Attacks in Children
More than half of all children with asthma will have an asthma “attack” each year. All children with asthma are different, but the treatments for asthma the same. We want to change this.
Children with asthma rarely have one symptom. Instead, most children have clusters of symptoms that may reflect different types of inflammation. For example, some children wheeze and have trouble breathing. Other children may cough or have airway mucous every day or at night. These symptom clusters are different for different children. However, current treatment for children for asthma is the same. We want to change this. This study will see whether children with different symptom clusters have different responses to asthma treatment. This study will also see if symptom clusters predict the occurrence of future asthma attacks.
We are looking for children 6 through 21 years of age with at least one asthma attack in the previous year for this clinical research study.
There are 3 options for participation in the Symptom Clusters study:
Option 1: 48 week study with 1 in person study visit, and a phone or email visit at weeks 24 and 48.
The in person visit will include a brief physical exam, breathing tests, questionnaires and a blood draw. In older children, there is also a collection of airway mucous.
Option 2: 48 week study with 5 in person visits.
Each in person visit includes a brief physical exam, breathing tests, questionnaires. Participants will receive a triamcinolone(steroid) injection at the first visit. Visits 1,2 and 5 will also include a blood draw. In older children, there is also a collection of airway mucous.
Option 3: 48 week study with 2 in person visits, and visits 3-5 completed by phone.
Each in person visit includes a brief physical exam, breathing tests, questionnaires. Participants will receive a triamcinolone(steroid) injection at the first visit. Visits 1 and 2 will also include a blood draw. In older children, there is also a collection of airway mucous.
Compensation for time and travel
If you are interested in the study, fill out the survey in the link below!
https://redcap.choa.org/redcap/surveys/?s=CCWKCJLAJ39TPHTP
Clinicaltrials.gov Identifier: NCT04002362
